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Core Purpose

The Central Government, acting under Section 6 of the Export (Quality Control and Inspection) Act, 1963, issues an order to further amend S.O. 4031 (E), dated 09th November, 2020, by prohibiting the use of certain antimicrobial medicinal products in Milch animals and during milk production/processing.

Detailed Summary

The Ministry of Commerce and Industry (Department of Commerce) issued Order S.O. 3224(E) on July 15, 2025, exercising powers conferred by section 6 of the Export (Quality Control and Inspection) Act, 1963 (22 of 1963). After consulting the Export Inspection Council, the Central Government further amends its previous Order, S.O. 4031 (E), dated 09th November, 2020. The amendment inserts two new clauses, (18) and (19), after clause (17) in the said Order. Clause (18) prohibits the use of any antimicrobial medicinal product for growth promotion or to increase yield in Milch animals. Clause (19) prohibits the use of a comprehensive list of antimicrobials and antimicrobial medicinal products for the treatment of Milch animals from where milk is procured, or at any stage of production and processing of Milk and Milk Products in establishment. This prohibited list includes 18 specific Antibiotics (e.g., Carboxypenicillins, Carbapenems, Glycopeptides, Oxazolidinones, Fidaxomicin), 18 Antivirals (e.g., Amantadine, Favipiravir, Molnupiravir, Oseltamivir), and 1 Antiprotozoal (Nitazoxanide). The principal order, S.O. 4031 (E), was originally published on November 9, 2020, and subsequently amended by S.O. 34(E) on December 29, 2023. This Order is signed by Siddharth Mahajan, Jt Secy.

Full Text

REGD. No. D. L.-33004/99 The Gazette of India CG-DL-E-16072025-264695 EXTRAORDINARY PART II-Section 3-Sub-section (ii) PUBLISHED BY AUTHORITY No. 3154] NEW DELHI, TUESDAY, JULY 15, 2025/ASHADHA 24, 1947 MINISTRY OF COMMERCE AND INDUSTRY (DEPARTMENT OF COMMERCE) ORDER New Delhi, the 15th July, 2025 S.O. 3224(E).— In exercise of the powers conferred by section 6 of the Export (Quality Control and Inspection) Act, 1963 (22 of 1963), the Central Government, after consulting the Export Inspection Council, hereby makes the following amendments further to amend the Order of the Government of India in the Ministry of Commerce and Industry, vide number S.O. 4031 (E), dated the 09th November, 2020, namely: - In the said Order, after clause (17), the following clauses shall be inserted, namely:- "(18) use of any antimicrobial medicinal product for the purpose of promoting growth or to increase yield shall be prohibited in Milch animals ; (19) the use of any of the following antimicrobials or group of antimicrobials and antimicrobial medicinal product shall be prohibited for treatment of Milch animals from where milk is procured, or at any stage of production and processing of Milk and Milk Products in establishment, namely:- (1) Antibiotics:- (a) Carboxypenicillins (b) Ureidopenicillins (c) Ceftobiprole (d) Ceftaroline (e) Combinations of cephalosporins with beta-lactamase inhibitors (f) Siderophore cephalosporins (g) Carbapenems (h) Penems (i) Monobactams (j) Phosphonic acid derivates (k) Glycopeptides (l) Lipopeptides (m) Oxazolidinones (n) Fidaxomicin (o) Plazomicin (p) Glycylcyclines (q) Eravacycline (r) Omadacycline (2)Antivirals:- (a) Amantadine (b) Baloxavir marboxil (c) Celgosivir (d) Favipiravir (e) Galidesivir (f) Lactimidomycin (g) Laninamivir (h) Methisazone or metisazone (i) Molnupiravir (j) Nitazoxanide (k) Oseltamivir (l) Peramivir (m) Ribavirin (n) Rimantadine (o) Tizoxanide (p) Triazavirin (q) Umifenovir (r) Zanamivir (3) Antiprotozoals:- (a) Nitazoxanide". [F. No. K-16012/2/2024 - Export Inspection] SIDDHARTH MAHAJAN, Jt Secy. Note: The principal order was published in the Gazette of India, Part II, Section 3, Sub-section (ii), vide number S.O. 4031 (E), dated the 09th November, 2020, and subsequently amended vide number S.O. 34(E), dated 29th December, 2023. Uploaded by Dte. of Printing at Government of India Press, Ring Road, Mayapuri, New Delhi-110064 and Published by the Controller of Publications, Delhi-110054. Digitally signed by GORAKHA NATH GORAKHA NATH YADAVA YADAVA Date: 2025.07.16 14:12:34 +05'30'

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